Table 2.

Relative Gene Expression in the ARC of DIO Mice After 4 Weeks on a HFD, IMF-HFD, LFD, or IMF-LFD Feeding Schedule (n = 8/Group)

Gene	HFD	IMF-HFD	LFD	IMF-LFD
Npy	0.94 ± 0.10	1.93 ± 0.27a,b	1.15 ± 0.11	2.04 ± 0.22a,b
Pomc	1.02 ± 0.07	0.81 ± 0.06a	0.74 ± 0.06a	0.57 ± 0.07a
Agrp	1.06 ± 0.13	1.33 ± 0.19	1.00 ± 0.13	1.28 ± 0.16
Glp1r	1.06 ± 0.14	1.31 ± 0.19	1.01 ± 0.13	1.28 ± 0.17
Ghsr	1.02 ± 0.08	1.73 ± 0.17a	1.41 ± 0.20	1.74 ± 0.17a
Adra1a	1.06 ± 0.13	1.34 ± 0.20	1.01 ± 0.13	1.30 ± 0.17
Adra1b	1.06 ± 0.13	1.31 ± 0.20	1.00 ± 0.13	1.28 ± 0.17
Adra2c	1.03 ± 0.10	1.13 ± 0.24	0.95 ± 0.17	0.79 ± 0.10

Abbreviations: Adra1A, α-adrenergic receptor 1A; Adra1B, α-adrenergic receptor 1B; Adra2C, α-adrenergic receptor 2C; GLP-1R, glucagon-like peptide 1 receptor. All gene expression data were expressed as an n-fold difference relative to the mean of the HFD group. Data are represented as means ± SEM.

^aP < .05 from HFD.

^bP < .05 from LFD.