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. 2016 Jan 27;3(1):e196. doi: 10.1212/NXI.0000000000000196

Figure 5. Flu immunization–induced changes in neutralizing Ab titers against 3 viral variants present in Afluria 2013 vaccine.

Figure 5

(A) The change in neutralizing Ab titers to all 3 viruses present in the Afluria vaccine between D0 (before vaccination), and 7 days (D7) and 180 days (D180) postvaccination graphed separately for control group (left panels) and DAC-HYP–treated patients (right panels). (B) Subgroup of control (left panel) and daclizumab-treated participants (right panel) who did not have preexisting Ab immunity at D0 to at least one of the viral variants are plotted separately, to demonstrate that all participants increased neutralizing Ab titers 7 days postvaccination (D7). The vertical box plots show the median and 25%–75% range, while the whiskers reflect minimum and maximum values for each diagnostic group. The scatter dot plots correspond to individual patient's data. *p < 0.05, **0.001 < p < 0.05, ***p < 0.001. Ab = antibody; DAC-HYP = daclizumab high-yield process.