Table V.
Differential distribution of genes related to urogenital tract development in cells from caput, corpus and cauda.
| Function | Gene ID | Gene name | Caput | Corpus | Cauda |
|---|---|---|---|---|---|
| AR related | AR | Androgen receptor | 2.85 | 0.40 | 0.23 |
| SRD5A2 | Steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) | 2.37 | 0.28 | 0.23 | |
| Outgrowth and branching of ureteric bud | GLI2 | GLI family zinc finger 2 | 0.86 | 0.15 | 0.21 |
| GREM1 | Gremlin 1, cysteine knot superfamily, homolog | 9.97 | 2.75 | 3.10 | |
| PAX2 | Paired box 2 | 19.78 | 4.95 | 4.36 | |
| PAX8 | Paired box 8 | 140.81 | 54.31 | 52.95 | |
| SALL1 | Sal-like 1 | 24.19 | 0.58 | 0.45 | |
| SHH | Sonic hedgehog homolog | 7.17 | 0.64 | 0.48 | |
| Others | ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 60.88 | 15.29 | 14.13 |
| CA2 | Carbonic anhydrase II | 40.72 | 9.79 | 7.21 | |
| CDC25B | Cell division cycle 25 homolog B | 35.46 | 12.72 | 14.07 | |
| CDH6 | Cadherin 6, type 2, K-cadherin | 72.83 | 2.40 | 1.34 | |
| CFTR | Cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) | 23.50 | 1.08 | 0.59 | |
| DZIP1 | DAZ interacting protein 1 | 17.94 | 3.83 | 4.78 | |
| FGF18 | Fibroblast growth factor 18 | 10.08 | 0.62 | 0.11 | |
| FGF9 | Fibroblast growth factor 9 (glia-activating factor) | 1.87 | 0.10 | 0.13 | |
| FGFR4 | Fibroblast growth factor receptor 4 | 9.38 | 0.44 | 0.45 | |
| FOXP2 | Forkhead box P2 | 0.92 | 0.07 | 0.03 | |
| HHIP | Hedgehog interacting protein | 6.90 | 0.43 | 0.35 | |
| HNF1A | HNF1 homeobox A | 3.59 | 0.23 | 0.16 | |
| HNF1B | HNF1 homeobox B | 49.17 | 11.95 | 12.04 | |
| HOOK1 | Hook homolog 1 | 17.34 | 3.14 | 2.63 | |
| MAPK8IP3 | Mitogen-activated protein kinase 8 interacting protein 3 | 40.01 | 17.71 | 17.43 | |
| PCSK5 | Proprotein convertase subtilisin/kexin type 5 | 8.16 | 0.83 | 0.73 | |
| PDE3A | Phosphodiesterase 3A, cGMP-inhibited | 1.60 | 0.28 | 0.22 | |
| PLA2G4A | Phospholipase A2, Group IVA (cytosolic, calcium-dependent) | 4.69 | 1.49 | 1.40 | |
| POU3F3 | POU class 3 homeobox 3 | 32.39 | 1.73 | 0.98 | |
| SPP1 | Secreted phosphoprotein 1 | 4700.7 | 41.88 | 33.60 | |
| SPRY2 | Sprouty homolog 2 | 33.62 | 9.12 | 9.03 | |
| STRA8 | Stimulated by retinoic acid gene 8 homolog | 2.82 | 0.03 | 0.04 | |
| VANGL2 | Vang-like 2 | 6.19 | 2.09 | 2.57 | |
| VGF | VGF nerve growth factor inducible | 39.28 | 0.63 | 0.32 | |
| WNT7A | Wingless-type MMTV integration site family, member 7A | 87.12 | 24.98 | 19.36 | |
| WWTR1 | WW domain containing transcription regulator 1 | 21.94 | 10.42 | 10.34 | |
| YBX2 | Y box binding protein 2 | 4.72 | 0.93 | 0.74 |
Genes classified according to their role in kidney development (Chai et al., 2013; Marcotte et al., 2014) (gene expression values as FPKM).