Table VI.
Innate immune response genes showing differentially high expression in the corpus and cauda (gene expression values as FPKM).
| Function | Gene ID | Gene name | Caput | Corpus | Cauda |
|---|---|---|---|---|---|
| Receptor-like proteins | TLR2 | Toll-like receptor 2 | 5.5 | 24.7 | 18.3 |
| TLR3 | Toll-like receptor 3 | 3.8 | 15.2 | 12.6 | |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 | 6.0 | 61.9 | 53.3 | |
| CALCOCO2 | Calcium binding and coiled-coil domain 2 | 15.4 | 35.8 | 34.1 | |
| IFIH1 | Interferon induced with helicase C domain 1 | 5.8 | 56.8 | 48.1 | |
| PGLYRP4 | Peptidoglycan recognition protein 4 | 0.1 | 2.4 | 3.4 | |
| Adapter protein | MYD88 | Myeloid differentiation primary response gene (88) | 17.2 | 53.4 | 47.2 |
| Other IL1 signaling components | IL1B | Interleukin 1, beta | 23.9 | 64.3 | 68.0 |
| IRAK2 | Interleukin-1 receptor-associated kinase 2 | 9.8 | 20.5 | 22.8 | |
| IL1A | Interleukin 1, alpha | 10.0 | 80.9 | 82.1 | |
| IL1RL1 | Interleukin 1 receptor-like 1 | 3.1 | 75.1 | 64.1 | |
| IL1RN | Interleukin 1 receptor antagonist | 18.3 | 219.2 | 241.0 | |
| Interleukin signaling | IL18R1 | Interleukin 18 receptor 1 | 0.9 | 5.1 | 4.8 |
| IL20RB | Interleukin 20 receptor beta | 1.4 | 20.4 | 22.3 | |
| Cytokine | IL17C | Interleukin 17C | 1.6 | 7.1 | 5.9 |
| Chemokines | CXCL10 | Chemokine (C-X-C motif) ligand 10 | 1.4 | 41.4 | 46.6 |
| CXCL11 | Chemokine (C-X-C motif) ligand 11 | 0.5 | 15.7 | 16.3 | |
| Antibacterial/antifungal/antimicrobial activity | HIST1H2BC | Histone cluster 1, H2bc | 4.5 | 59.9 | 41.8 |
| HIST1H2BK | Histone cluster 1, H2bk | 23.4 | 99.4 | 89.8 | |
| HIST2H2BE | Histone cluster 2, H2be | 2.1 | 15.6 | 13.5 | |
| RNASE7 | Ribonuclease, RNase A family, 7 | 0.7 | 8.8 | 7.8 | |
| IDO1 | Indoleamine 2,3-dioxygenase 1 | 14.6 | 105.1 | 89.7 | |
| Anti-bacterial peptides | S100A7 | S100 calcium binding protein A7 | 15.4 | 76.6 | 107.0 |
| S100A8 | S100 calcium binding protein A8 | 56.6 | 194.8 | 321.9 | |
| S100A9 | S100 calcium binding protein A9 | 414.4 | 2190.1 | 2464.7 | |
| Antiviral activity/response to viruses | IRF7 | Interferon regulatory factor 7 | 18.4 | 72.8 | 63.9 |
| MX1 | MX Dynamin-Like GTPase 1 | 30.5 | 356.5 | 328.4 | |
| MX2 | MX Dynamin-Like GTPase 2 | 0.2 | 14.8 | 12.6 | |
| RSAD2 | Radical S-adenosyl methionine domain containing 2 | 5.0 | 117.1 | 97.2 | |
| SAMHD1 | SAM domain and HD domain 1 | 4.9 | 27.0 | 23.1 | |
| Antigen presentation | TAP2 | Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) | 19.8 | 78.7 | 67.5 |