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Infarct size and blood flow after left common carotid artery (LCCA) occlusion. Staining revealed no apparent infarct in B6 brain slices (A) but infarcted tissue (pale area encircled) in 2 female Pgf −/− mice (B). The percentage of cerebral blood flow remaining after LCCA was significantly decreased in the Pgf −/− mice (C). * represents P < 0.05.
