TABLE 3.
Effect of in utero protein restriction, accelerated postnatal growth, and CoQ10 supplementation on serum and plasma measurements1
Control | Recuperated | Control CoQ10 | Recuperated CoQ10 | Effect of CoQ10 | |
Hepatic CoQ9, pmol/mg protein | 494 ± 28 | 497 ± 24 | 872.4 ± 79** | 1071 ± 266** | 0.003 |
Hepatic CoQ10, pmol/mg protein | 80 ± 7 | 78 ± 6 | 146 ± 17** | 102 ± 11** | 0.002 |
Fasting plasma glucose, mmol/L | 5.6 ± 0.2 | 5.3 ± 0.1 | 5.4 ± 0.3 | 5.24 ± 0.2 | 0.9 |
Serum cholesterol, mmol/L | 4.8 ± 0.5 | 4.9 ± 0.4 | 6.1 ± 0.7* | 5.9 ± 0.6* | 0.04 |
Serum trigyclerides, mmol/L | 3.8 ± 0.05 | 3.8 ± 0.4 | 4.2 ± 0.6* | 5.7 ± 0.7* | 0.02 |
Hepatic triglyceride content, g | 2.0 ± 0.2 | 2.3 ± 0.2 | 2.0 ± 0.1 | 2.0 ± 0.2 | 0.3 |
Values are means ± SEMs; n = 10/group. Data were analyzed by using 2-factor ANOVA and Duncan’s post hoc testing, where appropriate. The overall effects of maternal diet and interaction between maternal diet and CoQ10 supplementation were not significant for any of the variables reported in the table. *,**Effect of CoQ10: *P < 0.05, **P < 0.01. CoQ10, coenzyme Q.