Table 1.
Participant characteristics
| Oxytocin | Placebo | Statistics | |
|---|---|---|---|
| N | 23 | 18 | |
| Males (%) | 9 (39%) | 8 (44%) | χ2 = 0.1, df=1, P = 0.73b |
| Age | 39.7 ± 11.5 | 31.3 ± 11.5 | T(39) = −0.4, P = 0.66a |
| Type of trauma | χ2 = 2.2, df=3, P = 0.52 | ||
| Traffic accident (%) | 12 (52%) | 13 (72%) | |
| Accident at work/home (%) | 5 (22%) | 3 (17%) | |
| Interpersonal trauma (%) | 5 (22%) | 2 (11%) | |
| Other (%) | 1 (4%) | 0 (0%) | |
| Days between trauma and scan session | 8.7 ± 1.3 | 7.8 ± 2.9 | T(39) = 1.4, P = 0.18a |
| CAPS total | 46.8 ± 20.0 | 39.0 ± 17.8 | T(39) = 1.3, P = 0.20a |
| CAPS reexperiencing | 19.9 ± 9.5 | 13.1 ± 8.2 | T(39) = 2.4, P = 0.02a |
| CAPS avoidance | 10.2 ± 7.7 | 10.7 ± 5.6 | T(39) = −0.3, P = 0.80a |
| CAPS hyperarousal | 16.7 ± 7.6 | 15.2 ± 8.2 | T(39) = 0.6, P = 0.54a |
| Baseline anxiety VAS | med: 4.5 (range 0–53) | med: 4.0 (range 0–58) | U(38) = 195, P = 0.93c |
Means ( ± s.d.) or medians (and range) are listed for the oxytocin (OT) and placebo (PL) groups at baseline. CAPS, Clinical Administered PTSD scale; med median; OT, oxytocin; PL, placebo; VAS, visual analog scale; atested with two-sample t-test; btested with chi-square test; ctested with Mann-Whitney U-test.