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. Author manuscript; available in PMC: 2017 Jan 28.
Published in final edited form as: Cell. 2016 Jan 14;164(3):487–498. doi: 10.1016/j.cell.2015.12.038

Figure 4. Key Findings from the Stress Granule Proteome.

Figure 4

(A) Fluorescence microscopy of cells with Ded1-mCherry and Tys1-GFP or Rpb2-GFP after NaN3 treatment. (B) IF in NaAsO2 stressed GFP-G3BP U-2 OS cells using antibodies against YARS or FAM120A detected by a Cy5 labeled secondary antibody. Arrowheads within magnified areas indicate examples of overlap. Scale bars are 2μm. (C) Properties of the yeast and mammalian stress granule proteomes. (D) Yeast and mammalian stress granule ‘connectomes’ showing physical interactions amongst stress granule proteins. Red nodes represent known RNA binding proteins. See also Figure S5 and Tables S1, S2.