. Author manuscript; available in PMC: 2017 Mar 1.

Published in final edited form as: Eur J Nucl Med Mol Imaging. 2015 Sep 4;43(3):474–481. doi: 10.1007/s00259-015-3179-2

Table 2.

Correlation of measures of VMAT1 and VMAT2 protein expression with MIBG avidity.

	MIBG Avid (n = 56)^a	MIBG Non-Avid (n = 20)^a	p-value

VMAT1 Expression Intensity Category			0.91
0+	20 (36.4%)	8 (42.1%)
1+	5 (9.1%)	2 (10.5%)
2+	11 (20.0%)	4 (21.1%)
3+	19 (34.6%)	5 (26.3%)

Median Percent Cells Positive for VMAT1 (Range)	20 (0 – 99)	24 (0 – 100)	0.80

Median VMAT1 Composite Expression Score (Range)	48 (0 – 297)	45 (0 – 300)	0.76

VMAT2 Expression Intensity Category			0.26
0+	11 (19.6%)	8 (40%)
1+	3 (5.4%)	1 (5%)
2+	8 (14.3%)	3 (15%)
3+	34 (60.7%)	8 (40%)

Median Percent Cells Positive for VMAT2 (Range)	74 (0 – 100)	18 (0 – 99)	0.05

Median VMAT2 Composite Expression Score (Range)	216 (0 – 300)	45 (0 – 297)	0.04

Data for VMAT1 expression not available for one patient with MIBG avid tumor and one patient with MIBG non-avid tumor.