Table 2. Mean Health Related Quality of Life Scores at Baseline, Year 1, and Change Scores (Year 1 minus Baseline) by Randomization Assignment in the Women’s Health Initiative Dietary Modification Trial.
| Quality of Life Measure | n | Baseline | Intervention Means Year1 |
Change scoreb | n | Baseline | Comparison Means Year1 |
Change score | Mean | Differencea (95%CI) |
P-Valuec |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Global quality of life (0 worst to 10 best) | 17780 | 8.20 | 8.19 | −0.01 | 26407 | 8.18 | 8.11 | −0.10 | 0.09 | (0.07, 0.12) | <0.001 |
| General Healthd (0 worst to 100 best) | 17518 | 74.5 | 75.8 | 1.1 | 25985 | 74.3 | 73.9 | −0.7 | 1.7 | (1.5, 2.0) | <0.001 |
| Physical Functioningd (0 worst to 100 best) | 17329 | 81.1 | 81.9 | 0.6 | 25716 | 80.9 | 79.8 | −1.4 | 2.0 | (1.7, 2.3) | <0.001 |
| Vitality d (0 worst to 100 best) | 17559 | 62.6 | 64.7 | 2.0 | 25997 | 62.8 | 63.1 | 0.0 | 1.9 | (1.6, 2.2) | <0.001 |
| Role Physical d (0 worst to 100 best) | 17592 | 75.0 | 75.7 | 0.4 | 26054 | 74.5 | 72.9 | −2.0 | 2.4 | (1.7, 3.1) | <0.001 |
| Bodily Pain d (0 worst to 100 best) | 17808 | 74.8 | 74.9 | −0.2 | 26410 | 74.5 | 73.1 | −1.7 | 1.5 | (1.1, 1.9) | <0.001 |
| Social Functioning d (0 worst to 100 best) | 17713 | 90.2 | 88.9 | −1.5 | 26253 | 90.0 | 88.3 | −2.0 | 0.5 | (0.1, 0.9) | 0.01 |
| Role Emotional d (0 worst to 100 best) | 17612 | 84.3 | 84.1 | −0.7 | 26129 | 84.2 | 83.8 | −0.9 | 0.2 | (−0.4, 0.8) | 0.53 |
| Mental Health d (0 worst to 100 best) | 17472 | 79.0 | 80.4 | 1.1 | 25905 | 79.1 | 79.8 | 0.5 | 0.6 | (0.4, 0.8) | <0.001 |
| Self-Reported Health (1 worst to 5 best) | 17815 | 3.64 | 3.72 | 0.06 | 26456 | 3.64 | 3.61 | −0.05 | 0.10 | (0.09, 0.11) | <0.001 |
| Depressive Symptoms (0 worst to 18 best) | 17335 | 15.72 | 15.71 | −0.05 | 25698 | 15.69 | 15.61 | −0.12 | 0.07 | (0.02, 0.12) | 0.009 |
| 3MSEe (0 worst to 100 best) | 762 | 95.1 | 95.6 | 0.5 | 1155 | 95.0 | 95.3 | 0.6 | −0.1 | (−0.5, 0.3) | 0.69 |
| Sleep disturbance (0 worst to 20 best) | 17242 | 13.44 | 13.65 | 0.18 | 25583 | 13.43 | 13.44 | −0.01 | 0.19 | (0.12, 0.26) | <0.001 |
a
Mean difference of change scores (intervention minus comparison).
b
Missing data, at either baseline or Year 1, account for mean change scores not equal to Year 1 mean minus baseline mean.
c
Based on statistical significance of randomization assignment from linear model.
d
RAND-36 subscales
e
3MSE, modified mini-mental state examination