Table 1.
Subject characteristics
| All children | Subset with indoor air and dust fungal measures and assessment of: | ||
|---|---|---|---|
| Asthma/wheeze | Mold sensitization | ||
| (N=499) | (N=408) | (N=265) | |
| n (%) | n (%) | n (%) | |
|
| |||
| Health outcomes by age 13 | |||
| Ever asthma | 168 (33.7) | 136 (33.3) | 96 (36.2) |
| Ever wheeze | 390 (78.2) | 317 (77.7) | 204 (77.0) |
| Ever rhinitis | 181 (36.3) | 146 (35.8) | 106 (40.0) |
| Male sex | 266 (53.3) | 215 (52.7) | 150 (56.6) |
| Ethnicity | |||
| Caucasian | 375 (75.2) | 308 (75.5) | 218 (82.3) |
| African American | 59 (11.8) | 49 (12.0) | 22 (8.3) |
| Hispanic | 30 (6.0) | 19 (4.7) | 8 (3.0) |
| Asian | 28 (5.6) | 26 (6.4) | 12 (4.5) |
| Other | 7 (1.4) | 6 (1.5) | 5 (1.9) |
| Family income <$30k | 43 (8.6) | 32 (7.8) | 11 (4.2) |
| Parental history of asthma | 256 (51.3) | 211 (51.7) | 131 (49.4) |
| Maternal smoking during pregnancy | 32 (6.4) | 29 (7.1) | 21 (7.9) |
| Birth season | |||
| winter | 123 (24.7) | 104 (25.5) | 62 (23.4) |
| spring | 144 (28.9) | 113 (27.7) | 76 (28.7) |
| summer | 111 (22.2) | 89 (21.8) | 61 (23.0) |
| fall | 121 (24.3) | 102 (25.0) | 66 (24.9) |
| Cesarean birth | 116 (23.3) | 92 (22.6) | 60 (22.6) |
| Low birthweight quartile | 107 (21.4) | 83 (20.3) | 53 (20.0) |
| Low-normal gestational age (≤38.5wks) | 104 (20.8) | 87 (21.3) | 55 (20.8) |
| Building type | |||
| 1-family detached | 266 (53.3) | 214 (52.5) | 140 (52.8) |
| 1-family attached | 24 (4.8) | 20 (4.9) | 13 (4.9) |
| 2-family | 94 (18.8) | 83 (20.3) | 63 (23.8) |
| ≥ 3 apartments | 114 (22.9) | 90 (22.1) | 48 (18.1) |
| Elevated early-life (2–3mths) exposures | |||
| Home dampness | 219 (43.9) | 180 (44.1) | 119 (44.9) |
| Cockroach allergen (≥2 U/g max Bla g 1 or 2 in living room dust) | 109 (21.8) | 78 (19.1) | 44 (16.6) |
| Endotoxin (≥ median of measured samples = 81.3 EU/mg, in living room dust) | 202 (40.5) | 162 (39.7) | 111 (41.9) |
| Dust mite allergen (≥10μg/g Der p or f 1 baby’s bed) | 46 (9.2) | 40 (9.8) | 28 (10.6) |
| Cat allergen (≥8μg/g Fel d 1 home max) | 130 (26.1) | 109 (26.7) | 76 (28.7) |
| Detectable mouse urinary protein (living room dust) | 139 (27.9) | 114 (27.9) | 73 (27.6) |
| First year of life factors | |||
| Daycare attendance | 240 (48.1) | 199 (48.8) | 130 (49.1) |
| Bottle fed | 139 (27.9) | 111 (27.2) | 64 (24.2) |
| Lower respiratory illness | 133 (26.7) | 108 (26.5) | 72 (27.2) |
| Pet dog ownership | 82 (16.4) | 63 (15.4) | 43 (16.2) |