Skip to main content
. Author manuscript; available in PMC: 2016 Dec 7.
Published in final edited form as: Mol Pharm. 2015 Oct 23;12(12):4488–4497. doi: 10.1021/acs.molpharmaceut.5b00645

Figure 8.

Figure 8

Proposed mechanisms for H3-targeted polyplex transfer into the nucleus. Key regulators include importin-4, Sec61, as well as ER membrane mediated nuclear entry during mitosis.19