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. Author manuscript; available in PMC: 2017 Dec 1.
Published in final edited form as: J Tissue Eng Regen Med. 2015 Jul 31;11(6):1806–1819. doi: 10.1002/term.2078

Figure 4.

Figure 4

3D morphometric parameters of bone within the craniectomy defects at 4 weeks post-transplantation. The ROI was defined as follows: 5.0 mm circle, 50 cuts = 0.65 mm, total volume = 12.8 mm3. (A) BV/TV. (B) Tb.N. (C) Tb.Th. (D) Tb.Sp. The groups were: sham, vehicle control, BMP-2, Tet-Off-EV BMSCs, Tet-Off-EV BMSCs + BMP-2, Tet-Off-SDF-1β BMSCs or Tet-Off-SDF-1β BMSCs + BMP- 2; **p < 0.01, ***p < 0.0001 vs vehicle controls; bp < 0.01; cp < 0.0001 vs Tet-Off-EV or Tet-Off-SDF-1β BMSCs; #p < 0.05; $p < 0.01 vs Tet-Off-SDF-1β BMSCs; n = 10 animals/group