Table 2.
ΔGf | ||||||
---|---|---|---|---|---|---|
| ||||||
ROI | Change predicted From Baseline |
p | α ′ | Change-Change Correlation |
p | α ′ |
LPFC | .129 (.139) | .353 | .084 (.171) | .623. | ||
PFw | .214 (.080)* | .008 | .017 | .346 (.121)* | .004 | .017 |
Hc | .206 (.061)* | .001 | .017 | −.151 (.136) | .266 | |
PhG | .228 (.078)* | .003 | .017 | −.005 (.150) | .974 | |
CbH | .227 (.067)* | .001 | .017 | −.060 (.093) | .520 | |
VC | .102 (.096) | .288 | .033 (.123) | .788 |
Note. The results are from the models fitted separately for each cognitive construct, with all covariates used for statistical control: age at baseline, socioeconomic status, APOE ε4 allele, and vascular risk.
Abbreviations: ROI = Region of Interest volumes; LPFC = Lateral Prefrontal Cortex; PFw = Prefrontal subcortical white mater; Hc = Hippocampus; PhG = Parahippocampal Gyrus; CbH = Cerebellar hemispheres; VC = (Primary) Visual Cortex; Gf = Fluid Intelligence. Δ prefix indicates change. All volumes were divided by 1000 prior to analyses (to avoid estimation and scaling problems). Probabilities are adjusted for false discovery rate using Benjamini-Hochberg correction (α′), with a nominal α=.05.