(A) Biochemicals involved in the cholesterol pathway from control, Ldlr KO and Apoe KO brains of mice at 6 weeks and 12 weeks of age were compared through metabolomic analysis.
(B) Biochemicals from 6- and 12-week old control, Ldlr KO and Apoe KO mouse brains involved in the eicosanoid pathway.
Letters and lines indicate differences (p<0.05) between control and Ldlr KO or control and Apoe KO mice (n=6/group).