Table 2.
Characteristic | Case 1 | Case 1 | Case 2 | Case 3 | Case 4 |
---|---|---|---|---|---|
1st pregnancy | 2nd pregnancy | ||||
Time of diagnosis | At time of delivery | Previous pregnancy | At time of delivery | At time of delivery | Pre-pregnancy 7 months back |
Haemoglobin (gm/dL) | 11 | 10.2 | 8 | 9.2 | 7.5 |
TLC (/µL) | 354,000 | 169,000 | 140,000 | 64,000 | 147,000 |
Platelets (/µL) | 440,000 | 382,000 | 400,000 | 540,000 | 630,000 |
Drugs for CML at time of conception | None | Hydroxyurea till 8 weeks | None | None | Imatinib since 6 weeks pregnancy |
Phase of CML | CP (chronic phase) | AP (accelerated phase) | CP | CP | CP |
Splenomegaly | 10 cm | 8 cm | 12 | + | 13 |
Drugs for CML Postpartum/postabortal | Hydroxyurea | Imatinib | Hydroxyurea then imatinib | Hydroxyurea | Imatinib |