Table 1.
Characteristics of the eligible studies
| Author, year | Ethnicity | Sample size | SNP | Case | Control | Genotyping method | HWE (P) | Control from | NOS | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Case/control | MM | MW | WW | MM | MW | WW | |||||||
| Kim et al., 2005 | Asian | 85/231 | BsmI (G > A) | 2 | 11 | 72 | 3 | 60 | 168 | PCR-RFLP | 0.357 | HB | 7 |
| Lv et al., 2013 | Asian | 483/498 | TaqI (T > C) | 0 | 46 | 437 | 0 | 52 | 446 | PCR-RFLP | 0.219 | PB | 8 |
| Han et al., 2012 | Asian | 260/282 | BsmI (G > A) | 4 | 34 | 222 | 2 | 36 | 244 | PCR-RFLP | 0.599 | HB | 7 |
| FokI (T > C) | 114 | 124 | 22 | 109 | 126 | 47 | 0.306 | ||||||
| Liu et al., 2013 | Asian | 285/285 | ApaI (G > T) | 20 | 135 | 130 | 24 | 112 | 149 | PCR-RFLP | 0.651 | PB | 7 |
| TaqI (T > C) | 0 | 33 | 252 | 0 | 30 | 255 | 0.348 | ||||||
| Lin et al., 2014 | Asian | 700/792 | ApaI (G > T) | 105 | 361 | 234 | 141 | 401 | 250 | TaqMan | 0.365 | HB, PB | 6 |
| Török et al., 2013 | Caucasian | 100/109 | ApaI (G > T) | 42 | 43 | 15 | 42 | 46 | 21 | PCR-RFLP | 0.198 | HB | 7 |
| BsmI (G > A) | 24 | 49 | 27 | 25 | 57 | 27 | 0.629 | ||||||
| FokI (T > C) | 42 | 48 | 10 | 35 | 49 | 25 | 0.330 | ||||||
| TaqI (T > C) | 17 | 48 | 35 | 16 | 46 | 47 | 0.394 | ||||||
| Petersen et al., 2014 | Caucasian | 121/235 | ApaI (G > T) | 34 | 62 | 25 | 58 | 120 | 56 | TaqMan | 0.694 | HB | 6 |
| BsmI (G > A) | 20 | 53 | 48 | 34 | 117 | 84 | 0.510 | ||||||
| TaqI (T > C) | 20 | 54 | 47 | 34 | 119 | 81 | 0.360 | ||||||
SNP: Single nucleotide polymorphism; PB: Population-based; HB: Hospital-based; HWE: Hardy-Weinberg equilibrium; NOS: Newcastle-Ottawa Scale; PCR-RFLP: Polymerase chain reaction-restriction fragment length polymorphism.