Table 3.

Subgroup analysis of the association between the VDR gene polymorphism and PD

SNP	Model	Asian				Caucasian
		OR	95% CI	P	I2 (%)	OR	95% CI	P	I2 (%)
ApaI	T versus G	0.96	0.85–1.09	0.53	55	1.15	0.90–1.47	0.25	0
	TT versus GG	0.82	0.62–1.09	0.17	0	1.35	0.82–2.21	0.24	5
	TG versus GG	1.07	0.89–1.30	0.46	66	1.21	0.76–1.91	0.42	7
	TT + TG versus GG	1.02	0.85–1.23	0.81	67	1.26	0.82–1.93	0.30	0
	TT versus TG + GG	0.82	0.63–1.05	0.11	0	1.17	0.81–1.70	0.40	0
BsmI	A versus G	0.88	0.62–1.25	0.47	69	0.97	0.76–1.24	0.26	0
	AA versus GG	1.89	0.55–6.46	0.31	0	1.00	0.61–1.65	1.00	0
	AG versus GG	0.74	0.50–1.11	0.14	76	0.82	0.55–1.20	0.30	0
	AA + AG versus GG	0.80	0.55–1.18	0.26	75	0.86	0.60–1.24	0.42	0
	AA versus AG + GG	2.03	0.59–6.98	0.26	0	1.12	0.72–1.73	0.62	0
FokI	C versus T	1.34	1.04–1.72	–	–	1.61	1.09–2.40	–	–
	CC versus TT	2.23	1.26–3.95	–	–	3.00	1.27–7.08	–	–
	CT versus TT	2.10	1.19–3.69	–	–	2.50	1.06–5.64	–	–
	CC + CT versus TT	2.16	1.26–3.70	–	–	2.68	1.21–5.90	–	–
	CC versus CT + TT	1.24	0.88–1.75	–	–	1.53	0.87–2.69	–	–
TaqI	C versus T	0.98	0.71–1.35	0.90	0	1.06	0.83–1.36	0.64	7
	CC versus TT	–	–	–	0	1.16	0.70–1.93	0.57	0
	CT versus TT	0.98	0.71–1.36	0.90	0	0.99	0.77–1.26	0.89	55
	CC + CT versus TT	0.98	0.71–1.36	0.90	0	1.03	0.72–1.46	0.88	51
	CC versus CT + TT	–	–	–	0	1.18	0.74–1.88	0.50	0

OR: Odds ratio; CI: Confidence interval; VDR: Vitamin D receptor; PD: Parkinson’s disease; SNP: Single nucleotide polymorphism.