Table 6.
Distribution of mtDNA haplogroups after stratification by AAE <50
| Haplogroup* | PD (n = 32) n (%) | Control (n = 63) n (%) | P† | Logistic regression analysis | ||
|---|---|---|---|---|---|---|
| OR | 95% CI | P | ||||
| A | 3 (9.4) | 2 (3.2) | 0.428 | 3.037 | 0.459–20.117 | 0.249 |
| B‡ | 2 (6.3) | 16 (25.4) | 0.024 | 0.146 | 0.030–0.715 | 0.018 |
| C | 0 (0) | 3 (4.8) | 0.526 | 0.000 | 0.000–NA|| | 0.999 |
| D§ | 9 (28.1) | 6 (9.5) | 0.019 | 3.579 | 1.112–11.523 | 0.033 |
| F | 5 (15.6) | 9 (14.3) | 1.000 | 1.449 | 0.413–5.086 | 0.563 |
| G | 0 | 0 | – | – | – | – |
| Others | 13 (40.6) | 27 (42.9) | 0.835 | 0.953 | 0.393–2.313 | 0.916 |
*Fisher’s exact test for the overall haplogroup distribution: P = 0.032; †P values for 2 × 2 tables; ‡P < 0.05; §P < 0.05; ||NA: Not applicable; mtDNA: Mitochondrial DNA; AAE: Age at examination; OR: Odds ratio; CI: Confidence interval; PD: Parkinson’s disease.