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. 2016 Jan 30;7(1):2. doi: 10.1007/s13317-016-0073-2

Table 2.

Upper limit of normal (ULN), 97.5 % percentiles and cutoffs for autoantibody (autoAb) testing to tissue transglutaminase 2 (TG2)

ULN (U/mL) 97.5 % percentile (U/mL) Cutoff (U/mL)
ED (n = 68) 1.65 1.94 3.91a
BD (n = 91) 1.15 1.42 1.71b
ED + BD (n = 159) 1.41 1.54 3.91c

TG2autoAb were determined by CytoBead CeliAK in 130 pediatric/adolescent patients with celiac disease (CD) (<18 years) and 24 adult patients (≥18 years) as well as pediatric patients with eye disease (ED) and blood donors (BD) and subjected to receiver operating characteristics curve analysis. ULN (mean + 2 standard deviations), 97.5 % percentiles, and cutoffs were calculated. Total sample numbers can differ due to lack of human material or assay failure

aROC: CD <18 years vs ED

bROC: CD ≥18 years vs BD

cROC: CD vs ED + BD