Figure 4.

Morphological assessment of intraportally transplanted islets. (A, B) Representative sections of 1-month grafts consisting of islets precultured alone (A) or with adipose MSCs (B) for 3 days prior to intraportal transplantation. Images are representative of insulin staining for four animals in each transplant group. Original magnification: 400×. Scale bars: 25 µm. (C) Average area of islet graft sections; n = 53–102 graft sections from four animals in each transplant group; *p < 0.05 versus grafts consisting of islets precultured alone (Student’s t test).