Tab. I.
Studies on circulating miRNAs as potential biomarkers of ovarian cancer
Author/Reference no. | Year | Ovarian cancer type | Control | Type of sample | Up-regulated | Down-regulated |
---|---|---|---|---|---|---|
Taylor and Gercel-Taylor [50] | 2008 | Serous | Benign ovarian tumors | Exosomal serum miRNA | miR-21, miR-141, miR-200a, miR-200b, mir-200c, miR-203, miR-205, miR-214 | |
Resnick et al. [48] | 2008 | Generally epithelial ovarian cancer | Healthy controls | Serum miRNA | miR-21, miR-92, miR-93, miR-126, miR-29a | miR-155, miR-127, miR-99b |
Kan et al. [51] | 2012 | Serous (high grade) | Healthy controls | Serum miRNA | miR-200a, miR-200b, miR-200c | |
Chung et al. [52] | 2013 | Serous | Healthy controls | Serum miRNA | miR-132, miR-26a, Let-7b, mir-145 | |
Suryawanshi et al. [46] | 2013 | Endometrioid/Serous | Healthy controls/Endometriosis | Plasma miRNA | miR-16, miR-21, miR-191, miR-4284 | |
Ji et al. [53] | 2014 | Generally epithelial ovarian cancer | Healthy controls/Benign ovarian tumors | Serum miRNA | miR-22, miR-93 | |
Shapira et al. [54] | 2014 | Serous | Healthy controls/Benign ovarian tumors | Plasma miRNA | miR-106b, miR-126, miR-150, miR-17, miR-20a, and miR-92a |