Table II.
Inhibitory effects of MSC on the in vivo pulmonary metastasis of hepatocellular carcinoma.
Variable | MSC injection | No MSC injection | P-value |
---|---|---|---|
No. of animals | 8 | 9 | N/A |
Body weight, g | 21.99±2.90a | 22.08±1.69a | 0.918 |
Tumor weight, g | 2.90±0.80a | 2.86±0.72a | 0.906 |
Tumor weight/body weight, g | 0.14±0.05a | 0.13±0.04a | 0.754 |
Lung metastasis, % | 50% | 100% | 0.029 |
No. of lung metastases | 1.37±1.60a | 1.77±0.97a | 0.263 |
Cellular no. of metastases | 50.37±60.19a | 74.44±84.22a | 0.292 |
Student's t test was used to assess the statistical significance of differences in tumor weight, number of lung metastases and cellular numbers of metastases between the MSC injection group and no MSC injection group. Lung metastatic rate was evaluated using Fishers' exact test.
mean ± standard deviation. MSC, mesenchymal stem cells; N/A, not applicable.