Table III.
Cinicopathalogical variables in patients with HCC >10 cm and in patients with smaller tumors.
| Variable | No. cases | HCC <10 cm n (%) (n= 272) | HCC ≥10 cm n (%) (n= 127) | P-value |
|---|---|---|---|---|
| Age, years | ||||
| ≤48 | 207 | 237 (50.4) | 70 (55.1) | 0.376 |
| >48 | 192 | 135 (49.6) | 57 (44.9) | |
| Gender | ||||
| Female | 43 | 30 (11.0) | 13 (10.2) | 0.812 |
| Male | 356 | 242 (89.0) | 114 (89.8) | |
| HBsAg | ||||
| Negative | 80 | 55 (20.2) | 25 (19.7) | 0.901 |
| Positive | 319 | 217 (79.8) | 102 (80.3) | |
| Cirrhosis | ||||
| No | 86 | 49 (18.0) | 37 (29.1) | 0.012 |
| Yes | 313 | 223 (82.0) | 90 (70.9) | |
| Tumor encapsulation | ||||
| Complete | 193 | 142 (52.2) | 51 (40.2) | 0.025 |
| None | 206 | 130 (47.8) | 76 (59.8) | |
| Tumor no. | ||||
| Solitary | 259 | 191 (70.2) | 68 (53.5) | 0.001 |
| Multiple | 140 | 81 (29.8) | 59 (46.5) | |
| Vascular invasion | ||||
| Absent | 326 | 233 (85.7) | 93 (73.2) | 0.003 |
| Present | 73 | 39 (14.3) | 34 (26.8) | |
| Differentiation | ||||
| I–II | 285 | 194 (71.3) | 91 (71.7) | 0.946 |
| III–IV | 114 | 78 (28.7) | 36 (28.3) | |
| TNM stage | ||||
| I | 225 | 170 (62.5) | 55 (43.3) | <0.001 |
| II–III | 174 | 102 (37.5) | 72 (56.7) | |
| AFP, µg/l | ||||
| ≤25 | 127 | 88 (32.4) | 39 (30.7) | 0.743 |
| >25 | 272 | 184 (67.6) | 38 (69.3) | |
| Hospital mortality | 6 | 2 (0.7) | 4 (3.1) | 0.084 |
HCC, hepatocellular carcinoma; HBsAg, hepatitis B surface antigen; TNM, tumor-node-metastasis; AFP, α-fetoprotein.