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. 2015 Dec 11;4(2):261–267. doi: 10.3892/mco.2015.706

Table II.

Comparison of main clinicopathological characteristics among the three groups.

Patient no. (%)

Variables Group I (n=211) Group II (n=79) Group III (n=58) P-value
Gender 0.343
  Male 171 (81.0) 59 (74.7) 43 (74.1)
  Female 40 (19.0) 20 (25.3) 15 (25.9)
Age (years) 0.707
  ≤60 113 (53.6) 46 (58.2) 30 (51.7)
  >60 98 (46.4) 33 (41.8) 28 (48.3)
Smoking history 0.738
  Yes 148 (70.1) 59 (74.7) 42 (72.4)
  No 63 (29.9) 20 (25.3) 16 (27.6)
Predicted FEV1 0.106
  ≤60% 27 (12.8) 4 (5.1) 9 (15.5)
  >60% 184 (87.2) 75 (94.9) 49 (84.5)
Clinical T stage 0.002
  T1 19 (9.0) 11 (13.9) 4 (6.9)
  T2 131 (62.1) 32 (40.5) 33 (56.9)
  T3 41 (19.4) 33 (41.8) 18 (31.0)
  T4 20 (9.5) 3 (3.8) 3 (5.2)
Comorbidities 0.481
  Yes 80 (37.9) 24 (30.4) 20 (34.5)
  No 131 (62.1) 55 (69.6) 38 (65.5)
Clinical N2 levels 0.087
  Single 187 (88.6) 62 (78.5) 49 (84.5)
  Multiple 24 (11.4) 17 (21.5) 9 (15.5)
Clinical stage 0.252
  IIIA 192 (91.0) 76 (96.2) 55 (94.8)
  IIIB 19 (9.0) 3 (3.8) 3 (5.2)
Imaging response <0.001
  Objective response 199 (94.3) 7 (8.9) 58 (100.0)
  Stable disease 12 (5.7) 72 (91.1) 0 (0.0)
Type of operation <0.001
  Lobectomy 132 (62.6) 27 (34.2) 22 (37.9)
  Bilobectomy 37 (17.5) 11 (13.9) 7 (12.1)
  Pneumonectomy 42 (19.9) 41 (51.9) 29 (50.0)
Histology 0.002
  Adenocarcinoma 61 (28.9) 16 (20.3) 23 (39.7)
  Squamous cell carcinoma 127 (60.2) 40 (50.6) 28 (48.3)
  Adenosquamous carcinoma 17 (8.1) 20 (25.3) 6 (10.3)
  Others 6 (2.8) 3 (3.8) 1 (1.7)
N downstaging <0.001
  Yes 211 (100.0) 0 (0.0) 0 (0.0)
  No 0 (0.0) 79 (100.0) 58 (100.0)
Skip N2 metastasis <0.001
  Yes 0 (0.0) 32 (40.5) 28 (48.3)
  No 211 (100.0) 47 (59.5) 30 (51.7)

FEV1; forced expiratory volume in 1 sec; CT, computed tomography.