Table II.
Patient no. (%) | ||||
---|---|---|---|---|
Variables | Group I (n=211) | Group II (n=79) | Group III (n=58) | P-value |
Gender | 0.343 | |||
Male | 171 (81.0) | 59 (74.7) | 43 (74.1) | |
Female | 40 (19.0) | 20 (25.3) | 15 (25.9) | |
Age (years) | 0.707 | |||
≤60 | 113 (53.6) | 46 (58.2) | 30 (51.7) | |
>60 | 98 (46.4) | 33 (41.8) | 28 (48.3) | |
Smoking history | 0.738 | |||
Yes | 148 (70.1) | 59 (74.7) | 42 (72.4) | |
No | 63 (29.9) | 20 (25.3) | 16 (27.6) | |
Predicted FEV1 | 0.106 | |||
≤60% | 27 (12.8) | 4 (5.1) | 9 (15.5) | |
>60% | 184 (87.2) | 75 (94.9) | 49 (84.5) | |
Clinical T stage | 0.002 | |||
T1 | 19 (9.0) | 11 (13.9) | 4 (6.9) | |
T2 | 131 (62.1) | 32 (40.5) | 33 (56.9) | |
T3 | 41 (19.4) | 33 (41.8) | 18 (31.0) | |
T4 | 20 (9.5) | 3 (3.8) | 3 (5.2) | |
Comorbidities | 0.481 | |||
Yes | 80 (37.9) | 24 (30.4) | 20 (34.5) | |
No | 131 (62.1) | 55 (69.6) | 38 (65.5) | |
Clinical N2 levels | 0.087 | |||
Single | 187 (88.6) | 62 (78.5) | 49 (84.5) | |
Multiple | 24 (11.4) | 17 (21.5) | 9 (15.5) | |
Clinical stage | 0.252 | |||
IIIA | 192 (91.0) | 76 (96.2) | 55 (94.8) | |
IIIB | 19 (9.0) | 3 (3.8) | 3 (5.2) | |
Imaging response | <0.001 | |||
Objective response | 199 (94.3) | 7 (8.9) | 58 (100.0) | |
Stable disease | 12 (5.7) | 72 (91.1) | 0 (0.0) | |
Type of operation | <0.001 | |||
Lobectomy | 132 (62.6) | 27 (34.2) | 22 (37.9) | |
Bilobectomy | 37 (17.5) | 11 (13.9) | 7 (12.1) | |
Pneumonectomy | 42 (19.9) | 41 (51.9) | 29 (50.0) | |
Histology | 0.002 | |||
Adenocarcinoma | 61 (28.9) | 16 (20.3) | 23 (39.7) | |
Squamous cell carcinoma | 127 (60.2) | 40 (50.6) | 28 (48.3) | |
Adenosquamous carcinoma | 17 (8.1) | 20 (25.3) | 6 (10.3) | |
Others | 6 (2.8) | 3 (3.8) | 1 (1.7) | |
N downstaging | <0.001 | |||
Yes | 211 (100.0) | 0 (0.0) | 0 (0.0) | |
No | 0 (0.0) | 79 (100.0) | 58 (100.0) | |
Skip N2 metastasis | <0.001 | |||
Yes | 0 (0.0) | 32 (40.5) | 28 (48.3) | |
No | 211 (100.0) | 47 (59.5) | 30 (51.7) |
FEV1; forced expiratory volume in 1 sec; CT, computed tomography.