Table II.
Allele and genotype frequencies of Fas-670A>G polymorphism among patients and controls and their association with acute myeloid leukemia risk following adjustment.
| Genotype | Patients (n=98), n (%) | Controls (n=2,014), n (%) | ORa (95% CI) | P-value | ORb (95% CI) | P-value |
|---|---|---|---|---|---|---|
| AA | 17 (17.3) | 433 (21.5) | 1.00 | 0.58 | 1.00 | 0.79 |
| GA | 53 (54.1) | 1,013 (50.3) | 1.34 (0.77–2.35) | 0.30 | 1.21 (0.66–2.21) | 0.55 |
| GG | 28 (28.6) | 568 (28.2) | 1.27 (0.69–2.35) | 0.45 | 1.25 (0.64–2.45) | 0.51 |
| AA+GA | 81 (82.7) | 1,581 (78.5) | 1.32 (0.77–2.25) | 0.31 | 1.22 (0.69–2.18) | 0.50 |
ORs and 95% CIs were calculated by unconditional logistic regression adjusting for
a
age or
b
for drinking and smoking status. OR, odds ratio; CI, confidence interval.