Table IV.
Effect of treatment with Rx on serum ICAM-1 levels in diabetic rats at different time-points following hepatic I/R injury (ng/l).
| Groups | 1 h | 3 h | 5 h |
|---|---|---|---|
| DM + I/R | 263.3±38.2 | 465.7±31.4a | 689.3±37.8b |
| DM + Rx + I/R | 189.1±31.8c | 326.4±26.7a,c | 495.2±29.4b,c |
Rx, ruboxistaurin; ICAM-1, intercellular adhesion molecule 1; I/R, ischemia and reperfusion; DM, diabetes mellitus.
a
P<0.01 vs. the 1 h time-point
b
P<0.01 vs. the 3 h time-point and
c
P<0.01 vs. the DM + I/R group. Data are presented as the mean ± standard error of the mean (n=10).