Repeated dermal exposure to triclosan promotes adaptive immune responses in the skin draining LN. Total number of LN cells (A), frequencies (B) and numbers (C) of specific leukocyte subsets in the LN of OVA-sensitized mice after daily dosing with 0% (circle), 0.75% (square) or 3% (triangle) triclosan (n=4 mice). Data are representative of 3 independent studies. Bars represent the mean ± SEM, with statistical significance indicated as P ≤ .05 (*), P ≤ .01 (**), P ≤ .001 (***), and P ≤ .0001 (****).