Table 1.
Average PCs and phenotype values for self-reported ancestry groups in GWASs on hair color, tanning ability, and basal cell carcinoma
| Average PCs (SD)a | Hair color | Tanning ability | Basal cell carcinoma | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Self-reported European ancestry | 1 | 2 | N | Average | N | Average | Cases | Control | OR (95% CI) |
| Ashkenazi Jewish | −0.030 (0.009) | 0.003 (0.004) | 425 | 2.76 (0.73) | 579 | 2.30 (0.87) | 338 | 155 | 1.123 (1.074, 1.174) |
| Southern European | −0.003 (0.010) | −0.001 (0.011) | 1325 | 2.60 (0.74) | 1700 | 2.67 (0.90) | 1151 | 285 | Reference |
| Other Europeanb | 0.003 (0.005) | −0.001 (0.010) | 4963 | 2.39 (0.75) | 6559 | 2.54 (0.91) | 4074 | 1419 | 1.062 (1.035, 1.089) |
| Scandinavian | 0.005 (0.003) | 0.003 (0.009) | 727 | 2.08 (0.80) | 984 | 2.36 (0.91) | 610 | 227 | 1.075 (1.036, 1.116) |
| Total | 7440 | 9822 | 6173 | 2086 | |||||
a
Average PCs are derived from tanning ability GWAS samples, which has the largest sample size among the 3 GWAS analyzed here. Samples of the 3 GWAS are largely overlapped.
b
Other European refers to European American samples without self-reported European sub-population ancestry information.