Skip to main content
. 2016 Jan 16;22:40–60.

Table 3. Gene Ontology of genes upregulated in response to PNN reduction.

GO term Description P-value FDR q-value Enrichment Genes
Biologic Process
GO:0030334
regulation of cell migration
3.28E-08
3.79E-04
3.73
MMP10, EGFR, CXCL3, MMP9, STC1, CXCL1, UNC5C, HAS2, CXCL2, TRIB1, STRAP, LAMA3
GO:0006520
cellular amino acid metabolic process
9.41E-08
5.44E-04
4.8
EGLN1, PSAT1, PLA2G4E, GARS, MTHFD2L, GLS
GO:0030198
extracellular matrix organization
1.03E-07
3.98E-04
5.09
MMP13, MMP1, MMP10, MYO1E, ANXA2, MMP9, SERPINb5, CD44, LAMC!, HAS2, LAMC2, LAM3
GO:0043062
extracellular structure organization
1.03E-07
2.98E-04
5.09
MMP1, TIMP1, ACTN1. LAMC2, MMP13, TNC, SERPINB5, CD47, CD44, MMP9, ITGA2, SDC4
Molecular Function
GO:0044822
poly(A) RNA binding
2.03E-09
6.63E-06
1.63
UBC, ANXA2, NQo1, NAA38, RPS16, RRP12, STRAP
GO:0045236
CXCR chemokine receptor binding
2.18E-08
2.37E-05
64.04
CXCL3, CXCL1, CXCL2, YARS
GO:0004222 metalloendopeptidase activity 1.27E-06 1.03E-03 25.32 MMP10, ADAMS6, ADAM19, MMP13, MMP1, MMP9