Figure 7:

Application of radiomics to FDG-avid lymph nodes on PET and CT images in a patient with metastatic breast cancer. Left: Standard PET image shows there is little evidence of intranodal heterogeneity. Right: CT image shows calculation and display of the Haralick co-occurrence statistics with a 9 × 9 × 9 voxel matrix and clearly reveals some areas with lower co-occurrence (red), which have higher regional heterogeneity and would therefore be considered more suspicious for cancer. The results were used to select lymph nodes for image-informed biopsy.