Table 4.

Analysis of agonist-concentration response curves.

Parameter	Genotype			Significance (p)
	PlA1/A1	PlA1/A2	PlA2/A2
Maximum aggregation (%)	78 ± 5	77 ± 5	91 ± 4	0.008*
AUC (Arb)	103 ± 16	106 ± 16	122 ± 20	0.029*
Hill slope	2.88 ± 1.05	3.41 ± 1.40	3.693 ± 1.14	0.012*
logEC50 (Arb)	−5.44 ± 0.50	−5.49 ± 0.49	−5.42 ± 0.49	0.142*

Note: Pooled data for all agonist-concentration response curves generated by Optimul in response to ADP, collagen, adrenaline, ristocetin, U46619 and TRAP-6. Arbitrary units (Arb) presented for logEC₅₀ due to variation in units between agonists. Data presented as mean ± SEM. *p < 0.05

ADP: adenosine diphosphate; AUC: area under curve; EC₅₀: half-maximum effective concentration; SEM: standard error; TRAP-6: thrombin receptor-activating peptide 6.