Table I.
Neurological deficit score and infarct volume of rats 24, 36 and 72 h after the ischemia-reperfusion injury.
Neurological deficit | |||||
---|---|---|---|---|---|
Group | n | 24 h | 36 h | 72 h | Infarct volume, mm3 (n=5/group) |
Sham | 36 | 0 | 0 | 0 | 0 |
EPO-sham | 31 | 0 | 0 | 0 | 0 |
MCAO | 39 | 3.5±0.4a | 3.1±0.5a | 2.6±0.8a | 166±21a |
EPO-MCAO | 34 | 1.5±0.3a,b | 1.4±0.4a,b | 1.2±0.6a,b | 52±15a,b |
P<0.01 vs. the sham group;
P<0.01 vs. the MCAO group. Data are presented as the mean ± standard deviation. EPO, erythropoietin; MCAO, middle cerebral artery occlusion.