Table I.
QUADAS assessment for the eligible studies.
| Ogata-Kawata | Wang and | Basati | Toiyama | Kanaan | Zhang | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Item no. | Description | Liu et al (21) | et al (22) | Zhang (20) | et al (19) | Luo et al (23) | et al (24) | et al (25) | et al (26) | Du et al (27) |
| 1 | Was the spectrum of patients representative of the patients who will receive the test in practice? | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes |
| 2 | Were selection criteria clearly described? | Yes | No | Yes | Yes | Yes | Yes | Yes | Yes | Yes |
| 3 | Is the reference standard likely to correctly classify the target condition? | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes |
| 4 | Is the time period between reference standard and index test short enough to be reasonably sure that the target condition did not change between the two tests? | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes |
| 5 | Did the whole sample or a random selection of the sample receive verification using a reference standard? | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes |
| 6 | Did patients receive the same reference standard regardless of the index test result? | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes |
| 7 | Was the reference standard independent of the index test (i.e., the index test did not form part of the reference standard)? | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes |
| 8 | Was the execution of the index test described in sufficient detail to permit replication of the test? | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes |
| 9 | Was the execution of the reference standard described in sufficient detail to permit its replication? | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes |
| 10 | Were the index test results interpreted without knowledge of the results of the reference standard? | No | No | No | No | No | No | No | No | No |
| 11 | Were the reference standard results interpreted without knowledge of the results of the index test? | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes |
| 12 | Were the same clinical data available when test results were interpreted as would be available when the test is used in practice? | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes |
| 13 | Were uninterpretable/intermediate test results reported? | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes |
| 14 | Were withdrawals from the study explained? | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes |