Table III.
Analysis of prognostic factors by Cox regression analysis in postmenopausal ERα-positive breast cancer patients treated with endocrine therapy (n=140).
| Clinicopathological features | β coefficient | SEM | Wald value | P-value | Odds ratio | 95% CI |
|---|---|---|---|---|---|---|
| ERβ expression level | ||||||
| − | NA | NA | 8.729 | 0.013a | NA | NA |
| +/++ | −1.118 | 222.746 | 0.003 | 0.960 | <0.001 | 3.502–5.606 |
| +++ | 1.472 | 0.498 | 8.726 | 0.003a | 4.612 | 1.641–11.570 |
| Clinical stage | NA | NA | 5.422 | 0.066 | NA | NA |
| II | 1.388 | 0.784 | 3.136 | 0.077 | 4.006 | 0.862–18.612 |
| III | 2.040 | 0.877 | 5.410 | 0.020 | 7.693 | 1.379–42.937 |
| Chemotherapy | 0.333 | 0.574 | 0.336 | 0.562 | 1.395 | 0.453–4.295 |
| Radiotherapy | 0.099 | 0.609 | 0.026 | 0.871 | 1.104 | 0.335–3.642 |
a
Statistically significant (P<0.05). SEM, standard error of the mean; CI, confidence interval; ER, estrogen receptor; NA, not applicable.