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3-BrPA has a greater inhibitory effect in ErbB2-overexpressing breast cancer cells than control cells in nude mice. Pre-established 231V or 231ErbB2 tumor xenografts were treated with control (phosphate-buffered saline), 3-BrPA (10 mg/kg, twice/week for 3 weeks). Data are presented as the mean ± standard error of the mean of three independent experiments. *P<0.05, 231 ErbB2 PBS group vs. 231 ErbB2 3-BrPA group; #P<0.05, 231 V 3-BrPA group vs. 231 ErbB2 3-BrPA group.
