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. 2016 Jan 8;11(2):1335–1344. doi: 10.3892/ol.2016.4087

Figure 3.

Figure 3.

Effect of the hexane extract of Mangifera zeylanica on morphological changes and DNA fragmentation. (A) Morphological observations following acridine orange/ethidium bromide staining in three cancer cell lines treated with the hexane extract for 24 h: (a) MCF-7 cells, (b) MDA-MB-231 cells, and (c) SKOV-3 cells. (a1-c1) control cells; (a2-c2) cells treated with 50 µg/ml; (a3-c3) cells treated with 200 µg/ml; and (a4-c4) cells treated with 400 µg/ml of the hexane extract. (B) DNA fragmentation visualized by 2% agarose gel electrophoresis: M, 100 bp DNA ladder; 1, untreated control; 2, 400 µg/ml hexane extract; 3, 600 µg/ml hexane extract.