Figure 4. MiR-155 silencing inhibited collagen production in primary skin fibroblast with TGF-β stimulation.

Data were from three independent experiments. (a) MiR-155 was related with expression of type I collagen and α-SMA genes in skin fibroblasts from C57/BL6 mice. *P < 0.05, ANOVA. (b) Collagen concentrations in supernatant measured by Sircol assay. *P < 0.05 **P < 0.01, non-paired student’s t test.