Table V.
Risk of Adverse Outcomes by Infertility Diagnosis*
| Outcomes (all pluralities) | Male Factor | Endometriosis | Ovulation Disorders | Diminished Ovarian Reserve | Tubal Factors | Uterine Factors | Other Factors | Unexplained | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| (%) | (%) | AOR | 95% CI | (%) | AOR | 95% CI | (%) | AOR | 95% CI | (%) | AOR | 95% CI | (%) | AOR | 95% CI | (%) | AOR | 95% CI | (%) | AOR | 95% CI | |
| MATERNAL OUTCOMES | ||||||||||||||||||||||
| Pregnancy Hypertension | 15.1 | 11.7 | 0.61 | 0.41, 0.89 | 18.5 | 0.98 | 0.74, 1.30 | 26.0 | 1.30 | 0.92, 1.83 | 13.8 | 0.74 | 0.55, 1.01 | 11.2 | 0.55 | 0.26, 1.18 | 17.3 | 0.93 | 0.72, 1.21 | 13.6 | 0.87 | 0.70, 1.09 |
| Gestational Diabetes | 7.6 | 6.3 | 0.79 | 0.49, 1.26 | 14.0 | 1.77 | 1.28, 2.45 | 9.7 | 0.85 | 0.54, 1.34 | 10.8 | 1.19 | 0.84, 1.69 | 12.2 | 1.51 | 0.77, 2.97 | 7.9 | 0.88 | 0.63, 1.23 | 6.6 | 0.87 | 0.65, 1.16 |
| Prenatal Hospitalizations | ||||||||||||||||||||||
| Emergency Room Visits | 13.4 | 14.9 | 1.20 | 0.87, 1.66 | 15.2 | 1.14 | 0.86, 1.50 | 14.1 | 1.45 | 1.01, 2.08 | 17.9 | 1.18 | 0.90, 1.54 | 14.3 | 1.25 | 0.69, 2.28 | 12.8 | 1.11 | 0.86, 1.43 | 11.9 | 0.95 | 0.76, 1.19 |
| Observational Stays | 14.1 | 15.4 | 1.12 | 0.81, 1.55 | 15.8 | 1.06 | 0.81, 1.40 | 13.7 | 1.23 | 0.85, 1.78 | 13.7 | 0.93 | 0.70, 1.24 | 9.2 | 0.78 | 0.38, 1.59 | 11.2 | 0.90 | 0.69, 1.17 | 11.1 | 0.80 | 0.64, 1.01 |
| Hospital Admissions | 6.3 | 10.0 | 1.79 | 1.20, 2.68 | 12.4 | 2.01 | 1.44, 2.80 | 8.0 | 1.42 | 0.89, 2.27 | 8.7 | 1.49 | 1.04, 2.13 | 13.3 | 2.68 | 1.40, 5.15 | 9.0 | 1.66 | 1.21, 2.29 | 7.2 | 1.19 | 0.89, 1.60 |
| Primary Cesarean Delivery** | 47.6 | 50.7 | 1.11 | 0.84, 1.46 | 47.0 | 0.91 | 0.72, 1.15 | 57.1 | 0.95 | 0.71, 1.29 | 46.4 | 0.90 | 0.71, 1.15 | 66.3 | 1.96 | 1.15, 3.36 | 52.0 | 0.97 | 0.78, 1.20 | 50.2 | 1.09 | 0.91, 1.30 |
| INFANT OUTCOMES | ||||||||||||||||||||||
| Preterm | 21.9 | 23.4 | 1.02 | 0.75, 1.39 | 30.1 | 1.47 | 1.14, 1.89 | 28.4 | 1.19 | 0.86, 1.65 | 24.5 | 1.16 | 0.90, 1.50 | 25.5 | 1.30 | 0.74, 2.28 | 27.1 | 1.33 | 1.05,1.67 | 25.5 | 1.23 | 1.00, 1.50 |
| Low Birthweight | 16.9 | 14.9 | 0.71 | 0.50, 1.01 | 22.9 | 1.29 | 0.98, 1.69 | 21.1 | 1.14 | 0.80, 1.62 | 18.6 | 1.03 | 0.78, 1.36 | 23.5 | 1.59 | 0.90, 2.82 | 19.5 | 1.14 | 0.89, 1.47 | 19.4 | 1.10 | 0.89, 1.37 |
| Birthweight Zscore ≤1.28 (SGA) | 9.1 | 6.9 | 0.69 | 0.44, 1.07 | 10.3 | 1.09 | 0.79, 1.52 | 9.8 | 1.07 | 0.70, 1.64 | 8.7 | 0.86 | 0.61, 1.22 | 7.2 | 0.79 | 0.35, 1.77 | 10.0 | 1.12 | 0.83, 1.51 | 8.6 | 0.91 | 0.70, 1.19 |
| Birthweight Zscore ≥1.28 (LGA) | 9.4 | 9.9 | 1.14 | 0.77, 1.70 | 8.0 | 0.93 | 0.66, 1.33 | 8.1 | 0.73 | 0.47, 1.15 | 8.8 | 0.98 | 0.70, 1.39 | 10.3 | 1.10 | 0.55, 2.22 | 7.2 | 0.69 | 0.50, 0.96 | 8.7 | 1.00 | 0.77, 1.29 |
*
models adjusted for maternal and paternal age, race and ethnicity, and education; semen source; oocyte source; micromanipulation; embryo state; number of embryos transferred; maternal preexisting medical conditions (chronic hypertension and other diabetes); and plurality
**
models adjusted for all factors listed above, as well as breech/malpresentation and cephalopelvic disproportion, and excluding women with prior cesarean delivery (Significant AORs and 95% CIs are bolded for emphasis)