Table 1.
Entry | Substrate | R | Product | Yield (%)b |
1 | 1a | H | 2a | 70 |
2 | 1b | NH2 | 2b | 55 |
3 | 1c | SMe | 2c | 56 |
4 | 1d | OMe | 2d | 67 |
5 | 1e | Me | 2e | 79 |
6 | 1f | I | 2f | 77 |
7 | 1g | Br | 2g | 85 |
8 | 1h | Cl | 2h | 66 |
9 | 1i | F | 2i | 76 |
10 | 1j | CO2Et | 2j | 61 |
11 | 1k | CN | 2k | 79 |
12 | 1l | NO2 | 2l | 60 |
aReactions were performed on a 0.5 mmol scale in 1 mL of solvent using 1 atmosphere of O2 (balloon). bIsolated yields.