Table 1. Clinical manifestations and age of patients with invasive Streptococcus dysgalactiae subsp. equisimilis infection, Japan, April 2010–March 2013*.
| Clinical manifestation | No. (%) cases by age, y |
Total no. (%) cases | p value† | |||||
|---|---|---|---|---|---|---|---|---|
| <18 | 18–59 | ≥60 | ≥70 | ≥80 | ≥90 | |||
| Cellulitis | 1 (0.4) | 36 (15.4) | 26 (11.1) | 59 (25.2) | 78 (33.3) | 34 (14.5) | 234 (33.8) | 0.702 |
| Pneumonia | 2 (4.9) | 4 (9.8) | 5 (12.2) | 18 (43.9) | 12 (29.3) | 41 (5.9) | 0.006 | |
| Arthritis | 1 (2.1) | 11 (23.4) | 9 (19.1) | 13 (27.7) | 8 (17.0) | 5 (10.6) | 47 (6.8) | 0.076 |
| Abscess, noncutaneous | 1 (3.2) | 13 (41.9) | 5 (16.1) | 5 (16.1) | 5 (16.1) | 2 (6.5) | 31 (4.5) | <0.001 |
| Endocarditis | 3 (27.3) | 5 (45.5) | 2 (18.2) | 1 (9.1) | 11 (1.6) | – | ||
| Meningitis | 1 | 1 | 3 | 1 | 6 (0.9) | – | ||
| STSS | 1 | 1 | 1 | 3 (0.4) | – | |||
| Necrotizing fasciitis | 1 (6.3) | 3 (18.8) | 3 (18.8) | 3 (18.8) | 4 (25.0) | 2 (12.5) | 16 (2.3) | 0.803 |
| Cholangitis/peritonitis | 2 (14.3) | 1 (7.1) | 5 (35.7) | 5 (35.7) | 1 (7.1) | 14 (2.0) | 0.740 | |
| Osteomyelitis/spondylitis | 2 (14.3) | 5 (35.7) | 4 (28.6) | 3 (21.4) | 14 (2.0) | – | ||
| Bacteremia without primary focus | 1 (0.4) | 30 (11.1) | 39 (14.4) | 58 (21.5) | 97 (35.9) | 45 (16.7) | 270 (39.0) | 0.058 |
| Others‡ |
|
1 |
1 |
3 |
1 |
|
6 (0.9) |
– |
| Total | 6 (0.9) | 105 (15.2) | 94 (13.6) | 164 (23.7) | 221 (31.9) | 103 (14.9) | 693 (100) | |
*STSS, streptococcal toxic shock syndrome; –, not determined because of small number of strains. Blank cells indicate 0. †p values were calculated for differences between the 5 age groups, except the <18 y group. ‡Lymphangitis (n = 5) and keratitis (n = 1).