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. 2016 Feb;22(2):247–254. doi: 10.3201/eid2202.141732

Table 3. Correlation of emm type and macrolide or quinolone resistance genes among Streptococcus dysgalactiae subsp. equisimilis isolates, Japan, April 2010–March 2013*.

emm type Total no. strains No. (%) macrolide resistance
Total no. (%) resistance p value No. (%) quinolone resistance†
Total no. (%) resistance p value
erm(A) erm(B) mef(A) gyrA + parC parC
stG6792 188 10 (5.3) 7 (3.7) 7 (3.7) 24 (12.8) 0.018 2 (1.1) 3 (1.6) 5 (2.7) 0.950
stG485 92 12 (13.0) 1 (1.1) 2 (2.2) 15 (16.3) 0.565 4 (4.3) 4 (4.3) 0.257
stG245 74 1 (1.4) 37 (50.0) 38 (51.4) <0.001 1 (1.4) 1 (1.4) 0.476
stG652 47 6 (12.8) 1 (2.1) 7 (14.9) 0.513 3 (6.4) 3 (6.4) 0.091
seG10 43 10 (23.3) 8 (18.6) 1(2.3) 19 (44.2) <0.001 1 (2.3) 1 (2.3) 0.908
stG6 38 2 (5.3) 1 (2.6) 1 (2.6) 4 (10.5) 0.194 0
stG653 27 0 1 (3.7) 1 (3.7) 0.712
stG2078 26 6 (23.1) 1 (3.8) 7 (26.9) 0.656 1 (3.8) 1 (3.8) 0.725
stC36 25 1 (4.0) 1 (4.0) 2 (8.0) 0.169 0
stC74a 18 2 (11.1) 2 (11.1) 0.415 0
stG166b 17 0 0
stG480 16 2 (12.5) 2 (12.5) 0.534 0
stG5420 15 0 1 (6.7) 1 (6.7) 0.316
stC6979 13 1 (7.7) 1 (7.7) 0.312 0
stG4222 10 0 0
stG4974 10 2 (20.0) 2 (20.0) 0.900 1 (10.0) 1 (10.0) 0.138
Others 34 4 (11.8) 1 (2.9) 5 (14.7) 0.562 0
Total 693 55 (7.9) 62 (8.9) 11 (1.6) 128 (18.5) 11 (1.6) 7 (1.0) 18 (2.6)

*Dashes indicate p value not determined because of the small number of strains. Blank cells indicate 0.
†Mutations in gyrA gene: Ser81Phe (n = 8) and Ser81Tyr (n = 3). Mutation in parC genes: Ser79Phe (n = 16), Ser79Tyr (n = 1), Asp83Gly (n = 1).