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. 2015 Nov 18;48(1):55–66. doi: 10.3892/ijo.2015.3251

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Copyright: © Klacz et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Association between RASSF1A promoter methylation and expression at mRNA and protein levels in ccRCC tumor samples. Graphic presentation of multivariate regression analysis of RASSF1A expression pattern; promoter methylation, mRNA level and protein level. XYZ plot represent results of 58 T, C and 12 M biopsies; single results are shown by empty dots. Darkening area represents increasing association between variables (white area for <0.1 association to black area for >0.7 association). Regression analysis with methylation as an independent variable: b=−0.63, P<0.001.