Table 7. List of 51 consensus top binders from 1,000 peptide sequences against all seven 14-3-3 isoforms.
| No. | N-terminal | No. | N-terminal | No. | C-terminal | |||
|---|---|---|---|---|---|---|---|---|
| 1 | FFRpS/TXXXb | 20 | RLRpS/TXXX | 36 | XXXpS/TAGF | |||
| 2 | RAApS/TXXX | 21 | * | RPApS/TXXX | 37 | XXXpS/TAGP | ||
| 3 | *a | RAFpS/TXXX | 22 | * | RPKpS/TXXX | 38 | * | XXXpS/TAPF |
| 4 | * | RAKpS/TXXX | 23 | * | RPLpS/TXXX | 39 | * | XXXpS/TAPL |
| 5 | * | RALpS/TXXX | 24 | * | RPQpS/TXXX | 40 | * | XXXpS/TAPP |
| 6 | * | RAQpS/TXXX | 25 | * | RPRpS/TXXX | 41 | XXXpS/TAPR | |
| 7 | * | RARpS/TXXX | 26 | RPVpS/TXXX | 42 | * | XXXpS/TFPF | |
| 8 | * | RAVpS/TXXX | 27 | RRApS/TXXX | 43 | * | XXXpS/TFPL | |
| 9 | * | RFApS/TXXX | 28 | * | RRFpS/TXXX | 44 | XXXpS/TFPP | |
| 10 | * | RFFpS/TXXX | 29 | * | RRKpS/TXXX | 45 | XXXpS/TLPF | |
| 11 | * | RFKpS/TXXX | 30 | RRLpS/TXXX | 46 | * | XXXpS/TLPL | |
| 12 | * | RFRpS/TXXX | 31 | * | RRQpS/TXXX | 47 | XXXpS/TLPP | |
| 13 | RGApS/TXXX | 32 | RRRpS/TXXX | 48 | XXXpS/TLPR | |||
| 14 | RGKpS/TXXX | 33 | * | RVApS/TXXX | 49 | * | XXXpS/TVPF | |
| 15 | RGQpS/TXXX | 34 | * | RVKpS/TXXX | 50 | * | XXXpS/TVPL | |
| 16 | RGRpS/TXXX | 35 | * | RVRpS/TXXX | 51 | * | XXXpS/TVPP | |
| 17 | RGVpS/TXXX | |||||||
| 18 | RLApS/TXXX | |||||||
| 19 | RLKpS/TXXX |
a The motif with label * is the same with experimental binding sequences of H.S. Lu.
b The basic residue X means any of 20 amino acid types.