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. 2016 Feb 1;11(2):e0147428. doi: 10.1371/journal.pone.0147428

Fig 5. In vivo blocking of ICG-Glu-Glu-AE105 by uPA, the natural ligand.

Fig 5

(A) Representative images obtained by the IVIS Lumina XR at 710 nm showing a mouse receiving uPA simultaneously with ICG-Glu-Glu-AE105 resulting in decreased signal compared to a mouse only receiving ICG-Glu-Glu-AE105. (B) Two groups of mice (n = 4) were dynamically scanned with either ICG-Glu-Glu-AE105 + uPA or ICG-Glu-Glu-AE105. In all timepoints the two groups were significantly different with the group receiving only ICG-Glu-Glu-E105 having a 2 fold higher signal.