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. 2016 Feb 1;11(2):e0147867. doi: 10.1371/journal.pone.0147867

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© 2016 Reichhardt et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 3 — Paraffin-embedded placental tissue from healthy and pre-eclamptic (PE) pregnancies were stained for SALSA. Both healthy (A) and (B) and PE (C) and (D) sections are displayed with corresponding negative IgG-controls (Neg). Based on the morphology and location of the positively staining structures, SALSA primarily stains fibrin-type fibrinoids. (A) and (D) show staining of specific focal fibrinoid formations in apparently necrotic villous structures. Panel B shows an example of fibrinoid “gluing” of villi. (D) shows a larger necrotic area with massive fibrinoid formation. 200× magnifications.