Table 2.
Results of the orthogonal design
| Run number | A (°C) | B (mL/min) | C (L/h) | D | DL (%) | EE (%) |
|---|---|---|---|---|---|---|
| 1 | 190 | 12 | 700 | 1/1/0.33 | 3.07±0.13 | 7.15±0.46 |
| 2 | 190 | 8 | 400 | 2/1/0.33 | 2.70±1.78 | 3.39±1.13 |
| 3 | 190 | 14 | 300 | 3/1/0.67 | 2.44±1.31 | 3.77±1.23 |
| 4 | 170 | 12 | 400 | 3/1/0.67 | 0.21±0.04 | 0.50±0.13 |
| 5 | 170 | 8 | 300 | 1/1/0.33 | 3.14±2.31 | 5.01±1.45 |
| 6 | 170 | 14 | 700 | 2/1/0.33 | 0.42±0.12 | 0.71±0.22 |
| 7 | 150 | 12 | 300 | 2/1/0.33 | 4.93±0.16 | 8.71±0.23 |
| 8 | 150 | 8 | 700 | 3/1/0.67 | 4.03±0.57 | 7.78±0.32 |
| 9 | 150 | 14 | 400 | 1/1/0.33 | 5.08±0.15 | 9.53±0.69 |
Notes: A, inlet temperature; B, feeding rate; C, air flow rate; and D, CTS/PL/β-CD ratio. Data in the “DL” and “EE” columns presented as mean ± standard deviation.
Abbreviations: CTS, chitosan; PL, phospholipid; β-CD, β-cyclodextrin; DL, drug loading; EE, encapsulation efficiency.