Table III.
Sequence counts of IGHV genes and allelic variants associated with IGHJ6 alleles in VDJ rearrangements, and LRs for the inference of the presence of IGHV genes and allelic variants within the diplotypes of a representative individual
| Sequence Counts |
Presence of IGHV Genes on Chromosomes as Determined by LRs |
||||
|---|---|---|---|---|---|
| IGHJ6*02 | IGHJ6*03 | Chromosome 1a | Chromosome 2 | LR1 | |
| IGHV6-1*01b | 2 | 15 | x | ✓ | 6.60E+01 |
| IGHV1-2*02 | 2 | 28 | x | ✓ | 1.63E+06 |
| IGHV1-2*04 | 20 | 0 | ✓ | x | 5.82E+04 |
| IGHV1-3*01 | 42 | 3 | ✓ | x | 2.62E+07 |
| IGHV4-4*02 | 16 | 1 | ✓ | x | 1.35E+03 |
| IGHV2-5*01 | 0 | 12 | x | ✓ | 1.89E+03 |
| IGHV2-5*p11 | 2 | 0 | NDc | ND | |
| IGHV3-7*01 | 18 | 22 | ✓ | ✓ | 4.47E+18 |
| IGHV1-8*01 | 1 | 28 | x | ✓ | 1.84E+07 |
| IGHV3-9*01 | 1 | 13 | x | ✓ | 4.12E+02 |
| IGHV3-11*01 | 1 | 14 | x | ✓ | 1.28E+03 |
| IGHV3-15*01/02 | 0 | 26 | x | ✓ | 1.25E+07 |
| IGHV3-15*07 | 29 | 6 | ✓ | x | 6.63E+02 |
| IGHV1-18*01/p05 | 30 | 30 | ✓ | ✓ | 1.41E+33 |
a
Chromosome 1 is the IGHJ6*02-defined chromosome.
b
Data are shown for functional IGHV genes at the 3′ end of the IGHV locus.
c
No attempt was made to assign a gene or allelic variant to a chromosome where fewer than 10 VDJ rearrangements appeared to include that sequence.
x, Absent; ✓, present.