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. 2016 Feb 1;10(2):e0004368. doi: 10.1371/journal.pntd.0004368

Table 2. Comparison of the clinical effects and treatment of the patients who developed no neurotoxicity, mild neurotoxicity and severe neurotoxicity following common krait envenoming.

No neurotoxicity Mild neurotoxicity Severe neurotoxicity
Number of patients 8 8 17
Hours from bite to hospitalization: median (range) 3.0 (1.5–6.0) 3.0 (1.0–6.0) 3.3 (1.5–7.0)
Days of hospital stay: median (range) 2 (1–3) 3 (2–3) 8 (4–12)
Neurotoxicity
Maximum ptosis observed
    • Partial - 7 (87.5%) 5 (29.4%)
    • Complete - 1 (12.5%) 12 (70.6%)
Maximum ophthalmoplegia observed
    • Partial - 1 (12.5%) 3 (17.6%)
    • Complete - 0 14 (82.4%)
Strabismus - - 11 (64.7%)
Facial weakness - 1 (12.5%) 17 (100%)
Neck flexion weakness (power <5) - - 15 (88.2%)
Difficulty in swallowing - - 17 (100%)
Low pitched voice - - 12 (70.6%)
Tidal volume <250ml - - 17 (100%)
Reduced upper limb power (Power <5) - - 12 (70.6%)
Reduced lower limb power (power <5) - - 5 (29.4%)
Diminished or absent deep tendon reflexes 9 (52.9%)
Intubation and mechanical ventilation - - 17 (100%)
Autonomic features - - 6 (35.3%)
Other features of envenoming
Generalized myalgia 3 (32.7%) 2 (25%) 7 (41.2%)
Generalized muscle tenderness 2 (25%) 2 (25%) 7 (41.2%)
Local envenoming 5 (62.5%) 6 (75%) 9 (52.9%)
Non-specific systemic envenoming - 5 (62.5%) 13 (76.5%)
Treatment
Antivenom given - 6 (75%) 17 (100%)
Hours from bite to antivenom: median(range) - 7.5 (2.8–13.0) 3.5 (2.8–7.2)
Adverse reactions to antivenom - 6 (100%) 13 (76.5%)