Table 1.
Selected reports of intracameral antibiotics in cataract surgery
Series | n | Nation | Antibiotics | Rate without intracameral antibiotics (%) | Rate with intracameral antibiotics (%) | P-value |
---|---|---|---|---|---|---|
ESCRS10,* | 16,603 | Multiple | Cefuroxime | 0.18–0.23 | 0.025–0.050 | 0.005 |
Yu-Wai-Man et al12 | 36,743 | UK | Cefuroxime | 0.14 | 0.046 | 0.0068 |
Garat et al13 | 18,579 | Spain | Cefazolin | 0.39 | 0.032 | <0.0000001 |
Barreau et al16 | 5,115 | France | Cefuroxime | 1.24 | 0.044 | <0.0001 |
Romero-Aroca et al14 | 25,001 | Spain | Cefazolin | 0.63 | 0.05 | <0.001 |
Tan et al17 | 50,177 | Singapore | Cefazolin | 0.064 | 0.01 | <0.001 |
Friling et al20 | 464,996 | Sweden | Cefuroxime | 0.39 | 0.027 | <0.001 |
Matsuura et al21 | 34,752 | Japan | Moxifloxacin | 0.051 | 0.015 | 0.037 |
Shorstein et al18 | 16,264 | USA | Multiple | 0.31 | 0.014–0.14 | NR |
Rodriguez-Caravaca et al15 | 19,463 | Spain | Cefuroxime | 0.59 | 0.039 | <0.05 |
Beselga et al22 | 15,689 | Portugal | Cefuroxime | 0.26 | 0 | <0.05 |
Rudnisky et al25,** | 75,318 | Canada | Multiple | 0.03 | 0.03 | 0.90 |
Herrinton et al19 | 315,246 | USA | Multiple | 0.07–0.14 | 0.044 | NR |
Katz et al24 | 56,094 | Israel | Cefuroxime | 0.083 | 0.034 | 0.03 |
Rahman and Murphy23 | 16,975 | Ireland | Cefuroxime | 0.49 | 0.06 | <0.0001 |
Sharma et al26,** | 15,122 | India | Cefuroxime | 0.16 | 0.11 | 0.38 |
Notes:
Randomized clinical trial.
Series reporting no significant difference in endophthalmitis rates.
Abbreviations: ESCRS, European Society of Cataract and Refractive Surgeons; NR, not reported.