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. 2016 Jan 28;10:251–256. doi: 10.2147/OPTH.S100429

Table 1.

Selected reports of intracameral antibiotics in cataract surgery

Series n Nation Antibiotics Rate without intracameral antibiotics (%) Rate with intracameral antibiotics (%) P-value
ESCRS10,* 16,603 Multiple Cefuroxime 0.18–0.23 0.025–0.050 0.005
Yu-Wai-Man et al12 36,743 UK Cefuroxime 0.14 0.046 0.0068
Garat et al13 18,579 Spain Cefazolin 0.39 0.032 <0.0000001
Barreau et al16 5,115 France Cefuroxime 1.24 0.044 <0.0001
Romero-Aroca et al14 25,001 Spain Cefazolin 0.63 0.05 <0.001
Tan et al17 50,177 Singapore Cefazolin 0.064 0.01 <0.001
Friling et al20 464,996 Sweden Cefuroxime 0.39 0.027 <0.001
Matsuura et al21 34,752 Japan Moxifloxacin 0.051 0.015 0.037
Shorstein et al18 16,264 USA Multiple 0.31 0.014–0.14 NR
Rodriguez-Caravaca et al15 19,463 Spain Cefuroxime 0.59 0.039 <0.05
Beselga et al22 15,689 Portugal Cefuroxime 0.26 0 <0.05
Rudnisky et al25,** 75,318 Canada Multiple 0.03 0.03 0.90
Herrinton et al19 315,246 USA Multiple 0.07–0.14 0.044 NR
Katz et al24 56,094 Israel Cefuroxime 0.083 0.034 0.03
Rahman and Murphy23 16,975 Ireland Cefuroxime 0.49 0.06 <0.0001
Sharma et al26,** 15,122 India Cefuroxime 0.16 0.11 0.38

Notes:

*

Randomized clinical trial.

**

Series reporting no significant difference in endophthalmitis rates.

Abbreviations: ESCRS, European Society of Cataract and Refractive Surgeons; NR, not reported.